Description

Irinotecan Hydrochloride is a chemotherapy medication primarily used for the treatment of various cancers, most notably metastatic colorectal cancer. As a topoisomerase I inhibitor, Irinotecan works by interfering with the DNA replication process in cancer cells, effectively preventing them from reproducing and spreading. It is commonly used as part of combination chemotherapy regimens to improve treatment outcomes and reduce tumor growth.

Irinotecan Hydrochloride exerts its action by inhibiting the enzyme topoisomerase I, which is responsible for unwinding DNA to allow replication. By preventing the DNA from properly unwinding, Irinotecan induces DNA damage that ultimately leads to cancer cell death. This mechanism makes it particularly effective in treating cancers that rely on rapid cell division, such as colorectal, lung, and ovarian cancer.

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